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Cluster Report Photonics in the Capital Region Berlin-Brandenburg

  • Text
  • Imaging
  • Photonics
  • Berlin
  • Optical
  • Laser
  • Technologies
  • Optics
  • Microsystems
  • Components
  • Brandenburg

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68 Cluster Report Optics and Photonics – Biomedical and Ophthalmic Optics In the course of a research project on time-resolved optical nanoscopy, a wide-field fluorescence microscope with the ultra-high spatial and time resolution is being set up to perform nanoscopic fluorescence experiments using time- and location-correlated single photon detection. The technique is designated TSCSPC (time- and space-correlated single photon counting) or FLIN (fluorescence lifetime imaging nanoscopy). For example, the fluorescence lifetime distribution of photosynthetically active proteins in unicellular organisms can be detected with unprecedented precision in order to investigate important regulatory processes in photosynthesis. Using biological or chemical reference structures, the aim is to determine to what extent the technology is suitable for breaking through the diffraction limit caused by the spatial resolution in optical microscopy. A leading manufacturer of single photon detectors is Becker & Hickl GmbH. The company, also based in Berlin, not only offers highly efficient detectors, but also picosecond lasers and analysis software as well as its own confocal fluorescence microscope. www.becker-hickl.com Laser Technology in Medical Therapy For the surgeon, light can do so much more than just provide orientation. It can also be used as a tool, such as laser light which is increasingly being used for surgeries. Newport Spectra-Physics GmbH is one of the world’s largest companies in the field of laser surgery and has its German branch in Stahnsdorf, Brandenburg. The company mainly develops and produces diode-pumped femtosecond lasers. In addition to industrial applications, their applications extend to life and health sciences, microscopy, and biotechnology. The ultra-fast lasers are suitable for both LASIK surgery for eyes and other precision laser surgery. www.spectra-physics.com Laser systems have also proven to be a good alternative to other treatment methods in the destruction of gallstones and kidney stones. In clinical practice, interesting, unexpected effects have been seen here: certain laser types are better suited for the Asian market because the stones are darker there than in Western countries due to the different eating habits and their maximum absorption is therefore at different wavelengths. Berlin-based Limmer Laser GmbH specialises in the development and manufacture of medical lasers. The company’s products are used in almost all disciplines of human, dental, and veterinary medicine. The range extends from conventional CO 2 lasers to diode lasers and various special devices. Limmer Laser now offers fourth-generation CO 2 lasers, which deliver high performance and sharp beam diameters. www.limmerlaser.de/en In addition, there are companies that develop and manufacture peripherals and individual components for lasers, spectroscopic systems, and other diagnostic and therapeutic applications of optical principles in medicine. The Berliner Glas Group is one of the world’s leading companies when it comes to precise optical components, optomechanical and electro-optical modules, assemblies, and systems. Production and assembly take place worldwide, including Germany, Switzerland, and China. Berliner Glas is a driving force in the continuous further development of medical technology. The products and solutions are primarily found in the healthcare market segments of dental medicine, endoscopy, and ophthalmology, as well as in the field of life sciences. Berliner Glas manufactures many different optical systems: from prism assemblies and beam guidance systems to RGB LED cold light sources for endoillumination, endoscopy, and minimally invasive surgery. www.berlinerglas.com FCC FibreCableConnect GmbH manufactures laser cables and other fibre-optic connections, mainly for spectroscopy, biotechnology, and medicine. A specialty is the development of prototypes per special customer requirements and the transfer of the technology into serial production. Its products include high-performance fibre cables for industry, transmission fibre cables for medicine, optical fibre bundles and probes for spectroscopy, as well as optical fibre couplers. www.fibrecableconnect.de/en

Cluster Report Optics and Photonics – Biomedical and Ophthalmic Optics 69 OBERON GmbH Fiber Technologies develops and produces fibre-optic bundles, splitters, probes, and cables with different numerical apertures, coatings, and sheaths to apply for UV-VIS-NIR wavelengths in the range of 190 nm to 2,200 nm OBERON manufactures multi-arm fibre bundles, cross section transducers, reflection probes, transmission probes, and vacuum feedthroughs for various applications in spectroscopy, sensor technology, and analysis technology. www.oberonfiber.com Loptek GmbH & Co KG is another company in the region working with fibre optics, fibre probes, and optical measuring heads for use in medicine and biotechnology. Loptek actively advises its customers on the design of fibre-optic systems, individual design services, and completely new developments. escotec Lasertechnik GmbH offers lasermanufactured micro-joints, especially for stainless steel and titanium. www.loptek.de/en www.escotec.com/en In March 2017, CLS GmbH was founded as the German subsidiary of the Swedish company Clinical Laserthermia Systems AB in Berlin-Adlershof. The work being done in Berlin focuses on the development and production of diffusely radiating optical fibres, which are introduced into tumour tissues to destroy it thermally with laser light. Clinical studies are currently underway in Europe, including the immune response after laser therapy. Medical glass fibre for laser treatment of vascular diseases with an inverted cone for lateral optical radiation (without cap) © Fraunhofer IZM Under precise control with magnetic resonance imaging (MRI), the outer tissue of the tumour is heated to such an extent that the cancer cells die after a delay and antigens are released. The patient’s immune system is activated so that tumour cells circulating in the body are deactivated and metastases can no longer form. The method is suitable for the treatment of solid soft tissue tumours such as pancreatic, prostate, or renal cell cancers as well as metastases in the liver and lungs. www.clinicallaser.se/en/ Adjustment and gluing of a prism assembly for camera systems in medical technology © Berliner Glas KGaA

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